Symbol Name ID |
Srf
serum response factor MGI:106658 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Gastrointestinal hemorrhage |
Chylopericardium |
Pulmonary lymphangiomyomatosis |
Abnormality of the lymphatic system |
Lymphadenopathy |
Disease(s) Associated with SRF | |||||
lymphangioleiomyomatosis |
Mouse Phenotypes | cardiovascular system phenotype |
vascular smooth muscle hypotrophy |
abnormal myocardium layer morphology |
abnormal myocardial fiber morphology |
abnormal intercalated disk morphology |
trabecula carnea hypoplasia |
disorganized myocardium |
thin myocardium |
persistent truncus arteriosus |
abnormal fetal atrioventricular canal morphology |
abnormal interventricular septum morphology |
thin interventricular septum |
ventricular septal defect |
abnormal heart shape |
cardiac hypertrophy |
abnormal heart ventricle morphology |
increased heart left ventricle size |
abnormal interventricular groove morphology |
dilated heart ventricle |
abnormal pericardium morphology |
distended pericardium |
pericardial effusion |
cardiac fibrosis |
dilated cardiomyopathy |
internal hemorrhage |
decreased ventricle muscle contractility |
abnormal cardiac muscle relaxation |
irregular heartbeat |
increased cardiomyocyte apoptosis |
congestive heart failure |
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Availability | Mouse Genotype | ||||||||||||||||||||||||||||||
Srftm1Rmn/Srftm1Rmn Tg(Tagln-cre)1Jomm/0 (conditional) |
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Srftm1Rmn/Srftm1Rmn H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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Srftm1Zli/Srftm1Zli Tg(Myh7-cre)1Zli/0 (conditional) |
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Srftm1Zli/Srftm1Zli A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ (conditional) |
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Srftm2.1Nor/Srftm2.1Nor Tg(Myog-cre)1Eno/0 (conditional) |
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Srftm1Rjs/Srftm2.1Nor Tg(Myh6-cre)2182Mds/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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